SCHEMBL9746002

SCHEMBL9746002

CC[Sn](Cl)(CC)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.38
PSIP1 O75475 1/20 0.32
LMNA P02545 2/20 0.31
ATM Q13315 2/20 0.31
TAAR1 Q96RJ0 1/20 0.31
NR1I2 O75469 1/20 0.31
TSHR P16473 2/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30
RELA Q04206 1/20 0.30
KCNN4 O15554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9745552 0.86 TP53 (0.32) TP53RELA
SCHEMBL9746245 0.83 LTA4H (0.33) LMNATSHR
SCHEMBL9745240 0.80 TP53 (0.35) TP53PSIP1
SCHEMBL9747183 0.79 TP53 (0.38) TP53PSIP1LMNAATMTSHR
SCHEMBL9747213 0.77 TP53 (0.36) TP53PSIP1LMNATSHR
SCHEMBL8916517 0.77 LTA4H (0.35) LMNATSHR
SCHEMBL15375274 0.73 NPC1 (0.39) TP53LMNA
SCHEMBL25355509 0.72 TP53 (0.48) TP53PSIP1LMNAATMTSHR
SCHEMBL898908 0.72 TP53 (0.48) TP53PSIP1LMNAATMTSHR
SCHEMBL1029950 0.72 TP53 (0.41) TP53PSIP1LMNAATMTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5100762-A Radiation-sensitive polymer and radiation-sensitive composition containing the same MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1992-03-31 US disclosed