Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22963909 | 0.92 | MEN1 (0.61) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL24065618 | 0.90 | TSHR (0.58) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL20774473 | 0.87 | LMNA (0.68) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL21812209 | 0.87 | LMNA (0.68) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL21812210 | 0.87 | LMNA (0.68) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL20774373 | 0.87 | LMNA (0.68) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL20774363 | 0.87 | LMNA (0.68) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL20774365 | 0.87 | LMNA (0.68) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL20774362 | 0.87 | LMNA (0.68) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL22465753 | 0.87 | LMNA (0.68) | LMNAMEN1KMT2AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272918-B1 | DIFFUSION MATRIX FOR TRANSDERMAL DRUG ADMINISTRATION AND TRANSDERMAL DRUG DELIVERY DEVICES INCLUDING SAME | CYGNUS THERAPEUTIC SYSTEMS (US) | 1992-07-15 | — | — | EP | disclosed |
| US-4911916-A | Diffusion matrix for transdermal drug administration and transdermal drug delivery devices including same | CYGNUS RESEARCH CORPORATION (US) | 1990-03-27 | — | — | US | disclosed |
| EP-0272918-A2 | Diffusion matrix for transdermal drug administration and transdermal drug delivery devices including same | CYGNUS THERAPEUTIC SYSTEMS (US) | 1988-06-29 | — | — | EP | disclosed |