Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 7/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746867 | 0.89 | VEGFA (0.47) | VEGFASMN1; SMN2KDM4ESLC22A12FNTA | |
| SCHEMBL9747021 | 0.88 | VEGFA (0.45) | VEGFASMN1; SMN2KDM4ESLC22A12FNTA | |
| SCHEMBL9745883 | 0.88 | KDM4E (0.50) | SMN1; SMN2KDM4EARPOLBGAA | |
| SCHEMBL9746502 | 0.88 | VEGFA (0.48) | VEGFASMN1; SMN2KDM4ESLC22A12FNTA | |
| SCHEMBL9746284 | 0.87 | SMN1; SMN2 (0.48) | VEGFASMN1; SMN2KDM4ESLC22A12FNTA | |
| SCHEMBL9747117 | 0.86 | VEGFA (0.45) | VEGFASMN1; SMN2KDM4ESLC22A12FNTA | |
| SCHEMBL9746049 | 0.84 | POLB (0.46) | SMN1; SMN2KDM4EARPOLB | |
| SCHEMBL21352429 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4EARPOLBGAA | |
| SCHEMBL9746873 | 0.80 | SMN1; SMN2 (0.46) | VEGFASMN1; SMN2KDM4EARPOLB | |
| SCHEMBL9747099 | 0.80 | KDM4E (0.49) | VEGFASMN1; SMN2KDM4EARPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118431-A | Phthalonitriles and phthalocyanines as lubricity-enhancing additives | THE DOW CHEMICAL COMPANY (US) | 1992-06-02 | — | — | US | disclosed |
| US-5061388-A | Novel phthalonitriles and phthalocyanines as lubricity-enhancing additives | THE DOW CHEMICAL COMPANY (US) | 1991-10-29 | — | — | US | disclosed |