Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 1/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746284 | 0.96 | SMN1; SMN2 (0.48) | VEGFASLC22A12FNTAFNTBPGGT1B | |
| SCHEMBL9746867 | 0.93 | VEGFA (0.47) | VEGFASLC22A12FNTAFNTBPGGT1B | |
| SCHEMBL9747099 | 0.91 | KDM4E (0.49) | VEGFASMN1; SMN2KDM4EARALDH1A1 | |
| SCHEMBL21352429 | 0.89 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4EARALDH1A1CNR1 | |
| SCHEMBL9747021 | 0.89 | VEGFA (0.45) | VEGFASLC22A12FNTAFNTBPGGT1B | |
| SCHEMBL9747117 | 0.89 | VEGFA (0.45) | VEGFASLC22A12FNTAFNTBPGGT1B | |
| SCHEMBL9746156 | 0.88 | VEGFA (0.44) | VEGFASLC22A12FNTAFNTBPGGT1B | |
| SCHEMBL9746110 | 0.86 | SMN1; SMN2 (0.52) | FNTAFNTBPGGT1BSMN1; SMN2KDM4E | |
| SCHEMBL9746873 | 0.85 | SMN1; SMN2 (0.46) | VEGFASMN1; SMN2KDM4EARALDH1A1 | |
| SCHEMBL9746273 | 0.85 | SMN1; SMN2 (0.54) | FNTAFNTBPGGT1BSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118431-A | Phthalonitriles and phthalocyanines as lubricity-enhancing additives | THE DOW CHEMICAL COMPANY (US) | 1992-06-02 | — | — | US | disclosed |
| US-5061388-A | Novel phthalonitriles and phthalocyanines as lubricity-enhancing additives | THE DOW CHEMICAL COMPANY (US) | 1991-10-29 | — | — | US | disclosed |