Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6115118 | 1.00 | HDAC8 (0.33) | HDAC8HDAC6CES2CES1TSHR | |
| SCHEMBL6114649 | 1.00 | HDAC8 (0.33) | HDAC8HDAC6CES2CES1TSHR | |
| SCHEMBL620302 | 1.00 | HDAC8 (0.33) | HDAC8HDAC6CES2CES1TSHR | |
| SCHEMBL28229520 | 0.97 | HDAC8 (0.32) | HDAC8HDAC6CES2CES1TSHR | |
| SCHEMBL28230325 | 0.97 | HDAC8 (0.32) | HDAC8HDAC6CES2CES1TSHR | |
| SCHEMBL5576040 | 0.96 | TSHR (0.35) | TSHRALDH1A1 | |
| SCHEMBL6115251 | 0.89 | — | — | |
| SCHEMBL6114776 | 0.81 | — | — | |
| SCHEMBL9622146 | 0.79 | EPHX1 (0.35) | CES2CES1TSHREPHX1ALDH1A1 | |
| Cyclohexylsilanetriol SCHEMBL78580 | 0.79 | CES2 (0.33) | CES2CES1TSHREPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5099006-A | ompounds for use in paints, for waterproofing, as adhesion promoters, mordants, sizing agents and intermediates | RHONE-POULENC INC. (US) | 1992-03-24 | — | — | US | disclosed |
| US-5017694-A | With silanol-type compounds | RHONE-POULENC, INC. (US) | 1991-05-21 | — | — | US | disclosed |
| EP-0324671-A2 | Alkoxy-type derivatives of trivalent metals of group 3b, and their preparation | RHONE-POULENC CHIMIE (FR) | 1989-07-19 | — | — | EP | disclosed |
| EP-0319383-A2 | Process for the fabrication of cerium hydrocarbonsilyloxides by transetherification of cerium alkoxides | RHONE-POULENC CHIMIE (FR) | 1989-06-07 | — | — | EP | disclosed |
| EP-0319384-A2 | Cerium hydrocarbonsilyloxydes and process for their manufacture | RHONE-POULENC CHIMIE (FR) | 1989-06-07 | — | — | EP | disclosed |