Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | ATP4A | P20648 | 2/20 | 0.57 |
| ▸ | ATP4B | P51164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746953 | 0.90 | CYP3A4 (0.68) | CYP1A2CYP3A4CYP2D6CYP2C9ATP4A | |
| SCHEMBL9747667 | 0.88 | CYP1A2 (0.51) | CYP1A2CYP3A4CYP2D6CYP2C9ATP4A | |
| SCHEMBL9747746 | 0.88 | ATP4A (0.59) | CYP1A2CYP3A4CYP2D6CYP2C9ATP4A | |
| SCHEMBL10560331 | 0.86 | ATP4A (0.56) | CYP1A2CYP3A4CYP2D6CYP2C9ATP4A | |
| SCHEMBL9746970 | 0.85 | ATP4A (0.65) | CYP1A2CYP3A4CYP2D6CYP2C9ATP4A | |
| Hydrochloric Acid SCHEMBL10565262 | 0.85 | ATP4A (0.55) | CYP1A2CYP3A4CYP2D6CYP2C9ATP4A | |
| SCHEMBL9686421 | 0.85 | CYP3A4 (0.58) | CYP1A2CYP3A4CYP2D6CYP2C9ATP4A | |
| SCHEMBL10560189 | 0.85 | CYP1A2 (0.58) | CYP1A2CYP3A4CYP2D6CYP2C9ATP4A | |
| SCHEMBL9747165 | 0.85 | ATP4A (0.62) | CYP1A2CYP3A4CYP2D6CYP2C9ATP4A | |
| SCHEMBL9748644 | 0.84 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2D6CYP2C9ATP4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0204285-B1 | IMIDAZOHETEROCYCLIC COMPOUNDS PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-01-15 | — | — | EP | claimed |
| US-4725601-A | Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-02-16 | — | — | US | claimed |
| EP-0204285-A1 | Imidazoheterocyclic compounds processes for preparation thereof and pharmaceutical compositions comprising them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-12-10 | — | — | EP | claimed |
| EP-0204285-B1 | IMIDAZOHETEROCYCLIC COMPOUNDS PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |
| US-4725601-A | Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-02-16 | — | — | US | disclosed |
| EP-0204285-A1 | Imidazoheterocyclic compounds processes for preparation thereof and pharmaceutical compositions comprising them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-12-10 | — | — | EP | disclosed |