Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9191941 | 0.99 | SLC9A1 (0.67) | SLC9A1MAPTSLC6A9HPGDALDH1A1 | |
| SCHEMBL9196797 | 0.87 | SLC9A1 (0.66) | SLC9A1HPGDALDH1A1TSHRMEN1 | |
| SCHEMBL9436719 | 0.85 | SLC9A1 (0.68) | SLC9A1TSHRMEN1KMT2AGAA | |
| SCHEMBL3906519 | 0.79 | SLC9A1 (1.00) | SLC9A1 | |
| SCHEMBL29357040 | 0.79 | SLC9A1 (1.00) | SLC9A1 | |
| SCHEMBL8635738 | 0.78 | SLC9A1 (0.47) | SLC9A1SLC6A9ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL9436783 | 0.78 | SLC9A1 (0.98) | SLC9A1 | |
| Hydrochloric Acid SCHEMBL9436769 | 0.78 | SLC9A1 (0.98) | SLC9A1 | |
| SCHEMBL3906516 | 0.77 | SLC9A1 (0.64) | SLC9A1MAPTALDH1A1RAB9ANPC1 | |
| Sulfuric Acid SCHEMBL8816679 | 0.77 | SLC9A1 (0.95) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1049888-C | Benzoylguanidine, process for preparing same, their use as medicine and medicine containing same | HOECHST AG (DE) | 2000-03-01 | — | — | CN | disclosed |
| US-5091394-A | BENZOYLGUANIDINES, A PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |
| CN-1050018-A | Benzoylguanidines, they the preparation method, they are as the application of medicament and the medicament that contains them | HOECHST AG (DE) | 1991-03-20 | — | — | CN | disclosed |