SCHEMBL9746229

SCHEMBL9746229

C=C(C(=O)Oc1ccccc1)C(C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ELANE P08246 7/20 0.49
L3MBTL1 Q9Y468 4/20 0.46
ATM Q13315 3/20 0.46
TDP1 Q9NUW8 3/20 0.42
MAPT P10636 2/20 0.42
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 2/20 0.39
RAB9A P51151 2/20 0.39
KMT2A Q03164 2/20 0.39
NPC1 O15118 1/20 0.39
LMNA P02545 1/20 0.39
HPGD P15428 2/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9745988 0.89 ELANE (0.49) ELANEL3MBTL1ATMTDP1MAPT
SCHEMBL9746583 0.87 ELANE (0.47) ELANEL3MBTL1ATMTDP1MAPT
SCHEMBL9747390 0.85 ELANE (0.46) ELANEL3MBTL1ATMTDP1MAPT
SCHEMBL10787300 0.84 MAPT (0.47) ELANEL3MBTL1ATMTDP1MAPT
SCHEMBL23861753 0.83 ELANE (0.54) ELANEATMMAPTALDH1A1MEN1
SCHEMBL9746046 0.82 ELANE (0.46) ELANEL3MBTL1ATMTDP1MAPT
SCHEMBL28275181 0.82 ELANE (0.44) ELANEL3MBTL1ATMTDP1MAPT
SCHEMBL7738524 0.81 KMT2A (0.50) L3MBTL1TDP1MAPTALDH1A1MEN1
SCHEMBL9746277 0.81 ELANE (0.45) ELANEL3MBTL1ATMTDP1MAPT
SCHEMBL9745691 0.81 ELANE (0.45) ELANEL3MBTL1ATMTDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3583179-B1 METHOD FOR INCREASING THE ADHESIVE FORCE OF AN ADHESIVE TESA SE (DE) 2021-01-20 EP disclosed
EP-3615624-A1 ADHESIVE TAPE FOR SPLICING OF METAL SHEETS USED IN HIGH-TENSION, HIGH TEMPERATURE PROCESSES TESA SE (DE) 2020-03-04 EP disclosed
CN-110464847-A Anti-HER 2-drug conjugates DAIICHI SANKYO CO LTD 2019-11-19 CN disclosed
CN-105829346-B anti-HER 2 antibody-drug conjugates 第一三共株式会社 2019-08-23 CN disclosed
WO-2018197352-A1 ADHESIVE TAPE FOR SPLICING OF METAL SHEETS USED IN HIGH-TENSION, HIGH TEMPERATURE PROCESSES TESA SE (DE) 2018-11-01 WO disclosed
US-20180311928-A1 ADHESIVE TAPE FOR SPLICING OF METAL SHEETS USED IN HIGH-TENSION, HIGH TEMPERATURE PROCESSES TESA SE (DE) 2018-11-01 US disclosed
US-10100227-B2 Structured adhesive layer TESA SE (DE) 2018-10-16 US disclosed
CN-107434779-A Notch signal pathway inhibitors and its purposes in treatment of cancer 洛桑联邦理工学院(EPFL) 2017-12-05 CN disclosed
US-9676967-B2 Grooved adhesive tape TESA SE (DE) 2017-06-13 US disclosed
CN-104136027-B Notch signaling pathway inhibitors and their use in cancer treatment 洛桑联邦理工学院(EPFL) 2017-05-24 CN disclosed
US-20150225612-A1 GROOVED ADHESIVE TAPE TESA SE (DE) 2015-08-13 US disclosed
US-20150218423-A1 STRUCTURED ADHESIVE LAYER TESA SE (DE) 2015-08-06 US disclosed
US-5100762-A Radiation-sensitive polymer and radiation-sensitive composition containing the same MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1992-03-31 US disclosed
US-4806451-A MIXING FINE POWDER OR DISSOLVED DYE WITH POLYMER, COATING ON SUPPORT, AND DRYING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-02-21 US disclosed