Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632598 | 0.83 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2PDE10AGPBAR1ALOX5AP | |
| SCHEMBL9844652 | 0.83 | CYSLTR1 (0.69) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL8632478 | 0.83 | CYSLTR1 (0.45) | CYSLTR1CYSLTR2PDE10AGPBAR1ALOX5AP | |
| SCHEMBL8180239 | 0.77 | CYSLTR1 (0.51) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL8131833 | 0.76 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL8325040 | 0.75 | CYSLTR1 (0.74) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9121080 | 0.75 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9051963 | 0.74 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL8878133 | 0.74 | CYSLTR1 (0.51) | CYSLTR1CYSLTR2PDE10AGPBAR1ALOX5AP | |
| SCHEMBL22534449 | 0.73 | NR4A2 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104882-A | Leukotriene antagonists | MERCK FROSST CANADA, INC. (CA) | 1992-04-14 | — | — | US | disclosed |