Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.69 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.69 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.56 |
| ▸ | GPBAR1 | Q8TDU6 | 10/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746283 | 0.83 | CYSLTR1 (0.48) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL693506 | 0.83 | CYSLTR1 (0.76) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL10547998 | 0.82 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL8636013 | 0.82 | PDE10A (0.63) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL7717036 | 0.78 | CYSLTR1 (0.55) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL10543657 | 0.77 | CYSLTR1 (0.87) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL10512475 | 0.76 | PDE10A (0.77) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL27851428 | 0.76 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL7717119 | 0.76 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL10544473 | 0.76 | CYSLTR1 (0.84) | CYSLTR1CYSLTR2PDE10AGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102131801-A | 1, 2 disubstituted heterocyclic compounds | ENVIVO PHARMACEUTICALS INC | 2011-07-20 | — | — | CN | disclosed |
| EP-0414019-A2 | Subsituted N-(quinolin-2-yl-methoxy)benzylsulfonylureas | BAYER AG (DE) | 1991-02-27 | — | — | EP | disclosed |
| EP-0414078-A2 | Disubstituted (quinolin-2-yl-methoxy)-phenylacetic acid derivatives | BAYER AG (DE) | 1991-02-27 | — | — | EP | disclosed |
| EP-0344519-A1 | Substituted 4-(quinolin-2-yl-methoxy)phenyl-acetic-acid derivatives | BAYER AG (DE) | 1989-12-06 | — | — | EP | disclosed |
| EP-0339416-A1 | Optionally alpha-substituted 4-(quinolin-2-yl-methoxy)phenyl acetic acids and esters | BAYER AG (DE) | 1989-11-02 | — | — | EP | disclosed |