Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9745777 | 0.81 | TSHR (0.35) | TSHRTDP1CA4CA14CA12 | |
| SCHEMBL27752723 | 0.77 | TSHR (0.33) | TSHRTDP1CA4CA14CA12 | |
| SCHEMBL444720 | 0.73 | TSHR (0.39) | TSHRTDP1CA4CA14CA12 | |
| SCHEMBL10781916 | 0.73 | CA4 (0.39) | TSHRTDP1CA4CA14CA12 | |
| SCHEMBL11330453 | 0.73 | BBOX1 (0.40) | TSHRTDP1CA4CA14CA12 | |
| SCHEMBL1026637 | 0.73 | TSHR (0.39) | TSHRTDP1CA4CA14CA12 | |
| SCHEMBL28829375 | 0.73 | TSHR (0.39) | TSHRTDP1CA4CA14CA12 | |
| SCHEMBL70052 | 0.73 | CA4 (0.39) | TSHRTDP1CA4CA14CA12 | |
| SCHEMBL352235 | 0.73 | TSHR (0.39) | TSHRTDP1CA4CA14CA12 | |
| SCHEMBL9746969 | 0.73 | TP53 (0.36) | TSHRGLALMNAALDH1A1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5100762-A | Radiation-sensitive polymer and radiation-sensitive composition containing the same | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 1992-03-31 | — | — | US | disclosed |
| US-4975328-A | Adding a phosphoric acid release agent to the monomer mixture used in casting a polythiourethane | HOYA CORPORATION (JP) | 1990-12-04 | — | — | US | disclosed |