Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD4 | Q53EL6 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL9328037 | 0.82 | PDCD4 (0.45) | PDCD4ALDH1A1 | |
| SCHEMBL9328030 | 0.81 | TSHR (0.41) | PTPN1ALDH1A1CNR2 | |
| SCHEMBL8985076 | 0.79 | PDCD4 (0.47) | PDCD4 | |
| SCHEMBL14339054 | 0.79 | PDCD4 (0.47) | PDCD4 | |
| SCHEMBL9671381 | 0.79 | PDCD4 (0.47) | PDCD4 | |
| SCHEMBL9672604 | 0.79 | PDCD4 (0.47) | PDCD4 | |
| SCHEMBL8985069 | 0.78 | PDCD4 (0.39) | PDCD4 | |
| SCHEMBL9745763 | 0.78 | PDCD4 (0.38) | PDCD4 | |
| SCHEMBL9326875 | 0.78 | SMPD1 (0.46) | PDCD4PTPN1 | |
| SCHEMBL9670220 | 0.78 | DAGLA (0.41) | PDCD4PTPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089485-A | ANTI-INFLAMMATORY FURANONES | ALLERGAN, INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0369811-A2 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1990-05-23 | — | — | EP | disclosed |