Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD4 | Q53EL6 | 8/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | GLS2 | Q9UI32 | 3/20 | 0.32 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9672604 | 0.89 | PDCD4 (0.47) | PDCD4NAAAGLS2 | |
| SCHEMBL7294590 | 0.89 | PDCD4 (0.47) | PDCD4NAAAGLS2 | |
| SCHEMBL8985076 | 0.89 | PDCD4 (0.47) | PDCD4NAAAGLS2 | |
| SCHEMBL9671381 | 0.89 | PDCD4 (0.47) | PDCD4NAAAGLS2 | |
| SCHEMBL14339054 | 0.89 | PDCD4 (0.47) | PDCD4NAAAGLS2 | |
| Benzene SCHEMBL9328037 | 0.86 | PDCD4 (0.45) | PDCD4GLS2DAGLA | |
| SCHEMBL9325205 | 0.84 | PDCD4 (0.41) | PDCD4NAAADAGLA | |
| SCHEMBL9326904 | 0.84 | LMNA (0.42) | PDCD4 | |
| SCHEMBL9671761 | 0.83 | PDCD4 (0.43) | PDCD4NAAAGLS2 | |
| SCHEMBL9672394 | 0.83 | PDCD4 (0.41) | PDCD4GLS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089485-A | ANTI-INFLAMMATORY FURANONES | ALLERGAN, INC. (US) | 1992-02-18 | — | — | US | claimed |
| EP-0369811-A2 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1990-05-23 | — | — | EP | claimed |
| US-5541221-A | Pharmaceutical compositions and method for administering 3 and 4-substituted 2(5H)-furanones to a mammal for inhibiting bone loss | ALLERGAN (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0637240-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING 3 AND 4-SUBSTITUTED 2(5H)-FURANONES FOR INHIBITING BONE LOSS | ALLERGAN, INC. (US) | 1995-02-08 | — | — | EP | disclosed |
| US-5387606-A | Pharmaceutical compositions and method for administering 3 and 4-substituted 2(5H)-furanones to a mammal for inhibiting bone loss | ALLERGAN, INC. (US) | 1995-02-07 | — | — | US | disclosed |
| US-5268387-A | Containing ester or carbamate group | ALLERGAN, INC. (US) | 1993-12-07 | — | — | US | disclosed |
| WO-1993021915-A1 | PHARMACEUTICAL COMPOSITIONS FOR INHIBITING BONE LOSS CONTAINING 3 AND 4-SUBSTITUTED 2(5H)-FURANONES | ALLERGAN, INC. (US) | 1993-11-11 | — | — | WO | disclosed |
| US-5089485-A | ANTI-INFLAMMATORY FURANONES | ALLERGAN, INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0369811-A2 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1990-05-23 | — | — | EP | disclosed |