Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 4/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822629 | 0.89 | EPHX1 (0.44) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL7367448 | 0.85 | HDAC4 (0.41) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL9822874 | 0.81 | HDAC4 (0.45) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL9011358 | 0.81 | HDAC4 (0.40) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL9221868 | 0.79 | EPHX1 (0.48) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL1424928 | 0.79 | EPHX1 (0.48) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL7354951 | 0.79 | HDAC4 (0.42) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL9079109 | 0.79 | HDAC4 (0.42) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL7354944 | 0.79 | HDAC4 (0.42) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL9079107 | 0.79 | HDAC4 (0.42) | HDAC4HDAC1HDAC6EPHX1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091575-A | Renin inhibitor | ABBOTT LABORATORIES (US) | 1992-02-25 | — | — | US | disclosed |