Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 6/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14384998 | 0.93 | SMN1; SMN2 (0.39) | HDAC4HDAC1HDAC6CTSKCTSS | |
| SCHEMBL9221873 | 0.88 | EPHX1 (0.46) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL9822629 | 0.86 | EPHX1 (0.44) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL1859292 | 0.83 | HDAC4 (0.48) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL1414320 | 0.81 | HDAC4 (0.46) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL1414317 | 0.81 | HDAC4 (0.46) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL6625476 | 0.81 | HDAC4 (0.49) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL28463725 | 0.81 | HDAC4 (0.46) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL9746398 | 0.81 | HDAC4 (0.40) | HDAC4HDAC1HDAC6EPHX1CTSK | |
| SCHEMBL7367448 | 0.81 | HDAC4 (0.41) | HDAC4HDAC1HDAC6EPHX1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5036051-A | Renin inhibitors | ABBOTT LABORATORIES (US) | 1991-07-30 | — | — | US | disclosed |