Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.61 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SGMS2 | Q8NHU3 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.45 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.44 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125515 | 0.84 | LTA4H (0.61) | LTA4HMAPK14NPC1RAB9ASGMS2 | |
| SCHEMBL6080009 | 0.84 | NPC1 (0.61) | LTA4HMAPK14NPC1RAB9ASGMS2 | |
| SCHEMBL488757 | 0.81 | LTA4H (0.61) | LTA4HMAPK14NPC1RAB9ASGMS2 | |
| SCHEMBL488805 | 0.81 | LTA4H (0.61) | LTA4HMAPK14NPC1RAB9AHTT | |
| SCHEMBL6079375 | 0.81 | LTA4H (0.61) | LTA4HMAPK14NPC1RAB9ASGMS2 | |
| SCHEMBL15452368 | 0.81 | LTA4H (0.53) | LTA4HMAPK14NPC1RAB9ASGMS2 | |
| SCHEMBL10678765 | 0.80 | LTA4H (0.56) | LTA4HMAPK14NPC1RAB9ASGMS2 | |
| SCHEMBL9747613 | 0.80 | LTA4H (0.56) | LTA4HMAPK14NPC1RAB9ASGMS2 | |
| SCHEMBL10560687 | 0.80 | LTA4H (0.56) | LTA4HMAPK14NPC1RAB9ASGMS2 | |
| SCHEMBL10561222 | 0.80 | LTA4H (0.49) | LTA4HMAPK14NPC1RAB9ASGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0204285-B1 | IMIDAZOHETEROCYCLIC COMPOUNDS PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |
| US-4725601-A | Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-02-16 | — | — | US | disclosed |
| EP-0204285-A1 | Imidazoheterocyclic compounds processes for preparation thereof and pharmaceutical compositions comprising them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-12-10 | — | — | EP | disclosed |