Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HRAS | P01112 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746769 | 1.00 | LGALS8 (0.42) | LGALS8SIRT2SIRT1MAPK1HRAS | |
| SCHEMBL10524271 | 1.00 | LGALS8 (0.42) | LGALS8SIRT2SIRT1MAPK1HRAS | |
| SCHEMBL9745729 | 1.00 | LGALS8 (0.42) | LGALS8SIRT2SIRT1MAPK1HRAS | |
| SCHEMBL10523004 | 1.00 | LGALS8 (0.42) | LGALS8SIRT2SIRT1MAPK1HRAS | |
| SCHEMBL10522613 | 1.00 | LGALS8 (0.42) | LGALS8SIRT2SIRT1MAPK1HRAS | |
| SCHEMBL10523022 | 1.00 | LGALS8 (0.42) | LGALS8SIRT2SIRT1MAPK1HRAS | |
| SCHEMBL10522106 | 1.00 | LGALS8 (0.42) | LGALS8SIRT2SIRT1MAPK1HRAS | |
| SCHEMBL9745671 | 1.00 | LGALS8 (0.42) | LGALS8SIRT2SIRT1MAPK1HRAS | |
| SCHEMBL10521759 | 1.00 | LGALS8 (0.42) | LGALS8SIRT2SIRT1MAPK1HRAS | |
| SCHEMBL9745395 | 1.00 | LGALS8 (0.42) | LGALS8SIRT2SIRT1MAPK1HRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206037-B1 | CARBAMATES AND UREAS OF N-(2-AMINOACYLAMIDO-2-DESOXY-HEXOSYL) AMIDE, METHOD FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | BAYER AG (DE) | 1992-01-15 | — | — | EP | disclosed |
| US-4855283-A | IMMUNE SYSTEM STIMULANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-08-08 | — | — | US | disclosed |