Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746830 | 0.80 | TDP1 (0.50) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL14149481 | 0.79 | TDP1 (0.64) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL6618259 | 0.78 | TDP1 (0.44) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL6613577 | 0.78 | TDP1 (0.44) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL29549101 | 0.76 | KMT2A (0.52) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL22531716 | 0.76 | KMT2A (0.52) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL9746845 | 0.76 | AURKA (0.50) | ALDH1A1TDP1HPGDHSD17B10CA2 | |
| SCHEMBL7497022 | 0.74 | NR4A1 (0.42) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL6989267 | 0.73 | KMT2A (0.44) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL7497021 | 0.73 | AURKA (0.43) | KMT2AMAPTMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511152-A2 | Quinoxaline compounds, their preparation and use | NOVO NORDISK A/S (DK) | 1992-10-28 | — | — | EP | disclosed |