Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8689065 | 0.86 | TDP1 (0.57) | TDP1CTSBALDH1A1CYP3A4MAPT | |
| SCHEMBL11812795 | 0.81 | TDP1 (0.50) | TDP1CTSBALDH1A1CYP3A4MAPT | |
| SCHEMBL11781264 | 0.80 | TDP1 (0.50) | TDP1CTSBALDH1A1MAPTMEN1 | |
| SCHEMBL9747101 | 0.80 | KMT2A (0.46) | TDP1CTSBALDH1A1CYP3A4MAPT | |
| SCHEMBL26059203 | 0.79 | CTSB (0.64) | TDP1CTSBALDH1A1CYP3A4MAPT | |
| SCHEMBL8687514 | 0.77 | TDP1 (0.61) | TDP1CTSBALDH1A1CYP3A4MAPT | |
| SCHEMBL3179229 | 0.77 | TDP1 (0.46) | TDP1CTSBALDH1A1CYP3A4MAPT | |
| SCHEMBL3192020 | 0.77 | TDP1 (0.46) | TDP1ALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL1126918 | 0.74 | TDP1 (0.75) | TDP1CTSBALDH1A1CYP3A4MAPT | |
| SCHEMBL31689625 | 0.74 | TDP1 (0.75) | TDP1CTSBALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511152-A2 | Quinoxaline compounds, their preparation and use | NOVO NORDISK A/S (DK) | 1992-10-28 | — | — | EP | disclosed |