Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 9/20 | 0.55 |
| ▸ | WNT3A | P56704 | 7/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19287209 | 0.90 | CTNNB1 (0.53) | CTNNB1WNT3ACES2CES1LMNA | |
| SCHEMBL2470002 | 0.85 | CTNNB1 (0.71) | CTNNB1WNT3ACES2CES1LMNA | |
| SCHEMBL30695014 | 0.83 | CES2 (0.58) | CTNNB1WNT3ACES2CES1LMNA | |
| SCHEMBL225566 | 0.81 | CES2 (0.55) | CTNNB1WNT3ACES2CES1LMNA | |
| SCHEMBL30609612 | 0.81 | CTNNB1 (0.63) | CTNNB1WNT3ACES2CES1LMNA | |
| SCHEMBL4743860 | 0.81 | CTNNB1 (0.63) | CTNNB1WNT3ACES2CES1LMNA | |
| SCHEMBL6709434 | 0.79 | CTNNB1 (0.60) | CTNNB1WNT3ACES2CES1LMNA | |
| SCHEMBL27581934 | 0.78 | CTNNB1 (0.51) | CTNNB1WNT3ACES2CES1LMNA | |
| SCHEMBL6197288 | 0.78 | CTNNB1 (0.58) | CTNNB1WNT3ACES2CES1LMNA | |
| SCHEMBL30579595 | 0.78 | CTNNB1 (0.63) | CTNNB1WNT3ACES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192554-B1 | PEPTIDE DERIVATIVES INHIBITING RENIN AND ACID PROTEASES | SANOFI (FR) | 1992-01-02 | — | — | EP | claimed |
| EP-0211744-B1 | PEPTIDIC AMINO-ALCOHOL DERIVATIVES CONTAINING A TETRA-SUBSTITUTED CARBON ATOM, INHIBITORS OF RENIN AND OF ACID PROTEASES, PREPARATION PROCESS AND PHARMACEUTICAL COMPOSITIONS | SANOFI (FR) | 1991-12-04 | — | — | EP | claimed |
| EP-0193445-B1 | PEPTIDE DERIVATIVES, PEPSTATIN ANALOGUES, RENIN AND ACID-PROTEASE INHIBITORS | SANOFI (FR) | 1990-05-09 | — | — | EP | claimed |
| US-4840935-A | Peptide amino-alcohol derivatives containing a tetrasubstituted carbon atom, inhibiting renin and acid proteases, process for obtention and therapeutical use | SANOFI (FR) | 1989-06-20 | — | — | US | claimed |
| US-11396501-B2 | Heteroaryl compounds as CXCR4 inhibitors, composition and method using the same | CGENETECH (SUZHOU, CHINA) CO., LTD. (CN) | 2022-07-26 | — | — | US | disclosed |
| EP-3687540-A1 | HETEROARYL COMPOUNDS AS CXCR4 INHIBITORS, COMPOSITION AND METHOD USING THE SAME | CGeneTech (Suzhou, China) Co., Ltd. (CN) | 2020-08-05 | — | — | EP | disclosed |
| US-20200239439-A1 | HETEROARYL COMPOUNDS AS CXCR4 INHIBITORS, COMPOSITION AND METHOD USING THE SAME | Suzhou Yunxuan Yiyao Keji Youxian Gongsi (CN) | 2020-07-30 | — | — | US | disclosed |
| US-20200239439-A1 | HETEROARYL COMPOUNDS AS CXCR4 INHIBITORS, COMPOSITION AND METHOD USING THE SAME | Suzhou Yunxuan Yiyao Keji Youxian Gongsi (CN) | 2020-07-30 | — | — | US | disclosed |
| WO-2019060860-A1 | HETEROARYL COMPOUNDS AS CXCR4 INHIBITORS, COMPOSITION AND METHOD USING THE SAME | Suzhou Yunxuan Yiyao Keji Youxian Gongsi (CN) | 2019-03-28 | — | — | WO | disclosed |
| WO-2019060860-A1 | HETEROARYL COMPOUNDS AS CXCR4 INHIBITORS, COMPOSITION AND METHOD USING THE SAME | Suzhou Yunxuan Yiyao Keji Youxian Gongsi (CN) | 2019-03-28 | — | — | WO | disclosed |
| US-20110212053-A1 | PHOSPHATIDYLINOSITOL 3 KINASE INHIBITORS | PROGENICS PHARMACEUTICALS, INC. | 2011-09-01 | — | — | US | disclosed |
| US-4840935-A | Peptide amino-alcohol derivatives containing a tetrasubstituted carbon atom, inhibiting renin and acid proteases, process for obtention and therapeutical use | SANOFI (FR) | 1989-06-20 | — | — | US | disclosed |
| US-4746648-A | HYPOTENSIVE, ANTIULCER | Sanofi, Institut National de la Recherche Medicale (FR) | 1988-05-24 | — | — | US | disclosed |
| US-4725580-A | ARTERIAL TENSION | SANOFI (FR) | 1988-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11396501-B2 | Heteroaryl compounds as CXCR4 inhibitors, composition and method using the same | CXCR4, CXCL12, CXCR1 | CTNNB1 137/4885WNT3A 362/4885CES2 1347/4885 |
| US-20110212053-A1 | PHOSPHATIDYLINOSITOL 3 KINASE INHIBITORS | PIK3CA, AKT1, PIK3R5 | CTNNB1 1635/4885WNT3A 1415/4885CES2 3192/4885 |
| US-20200239439-A1 | HETEROARYL COMPOUNDS AS CXCR4 INHIBITORS, COMPOSITION AND METHOD USING THE SAME | CXCR4, CXCL12, CXCR1 | CTNNB1 137/4885WNT3A 362/4885CES2 1347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.