Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9745855 | 0.89 | ALOX5 (0.47) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL9747943 | 0.80 | POLB (0.51) | HPGDHTTKDM4EALOX5MGLL | |
| SCHEMBL31540970 | 0.80 | NPC1 (0.72) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL2863890 | 0.80 | HPGD (0.47) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL28166975 | 0.79 | PSMB5 (0.48) | PSMB5HSD11B1GCGR | |
| SCHEMBL8706623 | 0.79 | TYR (0.61) | HPGDHTTKDM4EALOX5TRPV1 | |
| SCHEMBL2654018 | 0.78 | NPC1 (0.46) | NPC1HPGDMAPK1HTTRAB9A | |
| Benzene SCHEMBL28002837 | 0.78 | HTT (0.57) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL12457001 | 0.78 | TYR (0.46) | HTTALOX5TRPV1MGLLTYR | |
| SCHEMBL2868017 | 0.76 | BACE1 (0.47) | NPC1HPGDMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |