Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 10/20 | 0.45 |
| ▸ | PNP | P00491 | 8/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10598150 | 0.84 | HPRT1 (0.44) | HPRT1PNPXDHMEN1KMT2A | |
| SCHEMBL10400436 | 0.82 | BLM (0.55) | HPRT1PNPMEN1KMT2A | |
| SCHEMBL9662638 | 0.82 | BLM (0.55) | HPRT1PNPMEN1KMT2A | |
| SCHEMBL10564406 | 0.82 | BLM (0.55) | HPRT1PNPMEN1KMT2A | |
| SCHEMBL8990385 | 0.81 | HPRT1 (0.57) | HPRT1PNP | |
| SCHEMBL8990380 | 0.81 | HPRT1 (0.57) | HPRT1PNP | |
| SCHEMBL8743536 | 0.79 | PNP (0.51) | HPRT1PNPXDHMEN1KMT2A | |
| SCHEMBL8743558 | 0.78 | PNP (0.50) | HPRT1PNPXDHMEN1KMT2A | |
| SCHEMBL10994419 | 0.77 | HPRT1 (0.40) | HPRT1PNPXDH | |
| SCHEMBL16056622 | 0.77 | HPRT1 (0.43) | HPRT1PNPXDHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098906-A | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-4921859-A | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1990-05-01 | — | — | US | disclosed |
| EP-0145207-A1 | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1985-06-19 | — | — | EP | disclosed |