Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 13/20 | 0.66 |
| ▸ | CYP11B2 | P19099 | 11/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.58 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | QPCT | Q16769 | 1/20 | 0.58 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.58 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11700956 | 0.85 | CYP19A1 (0.64) | CYP11B1CYP11B2CYP19A1TBXAS1 | |
| SCHEMBL12245400 | 0.85 | CYP11B1 (0.66) | CYP11B1CYP11B2ADRA2CCYP19A1TBXAS1 | |
| SCHEMBL394308 | 0.84 | CYP11B1 (0.83) | CYP11B1CYP11B2ADRA2CCYP19A1TBXAS1 | |
| SCHEMBL28140204 | 0.81 | CYP11B1 (0.68) | CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2 | |
| SCHEMBL9747422 | 0.80 | CYP11B1 (1.00) | CYP11B1CYP11B2ADRA2CCYP19A1TBXAS1 | |
| SCHEMBL12299569 | 0.80 | CYP11B1 (0.71) | CYP11B1CYP11B2ADRA2CCYP19A1TBXAS1 | |
| SCHEMBL8070045 | 0.79 | CYP11B1 (0.61) | CYP11B1CYP11B2ADRA2CCYP19A1TBXAS1 | |
| Hydrochloric Acid SCHEMBL11081394 | 0.78 | EPHX1 (0.46) | CYP11B1CYP11B2ADRA2CCYP19A1TBXAS1 | |
| SCHEMBL14315492 | 0.78 | CYP11B1 (0.71) | CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2 | |
| SCHEMBL21950448 | 0.78 | CYP11B1 (0.50) | CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922386-A | 1,4 disubstituted imidazolium derivatives | 大日本住友制药株式会社 | 2018-04-17 | — | — | CN | disclosed |
| CN-107922348-A | Bicyclic heterocyclic amide derivatives | 大日本住友制药株式会社 | 2018-04-17 | — | — | CN | disclosed |
| US-5100890-A | Antidepressants, Fungicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | disclosed |
| EP-0218118-B1 | ARYLMETHYL AZOLES AND THEIR SALTS, METHOD FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-18 | — | — | EP | disclosed |
| US-5023357-A | Arylmethylazole preparation processes | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-11 | — | — | US | disclosed |
| US-4876354-A | FUNGICIDES, ANTIDEPRESSANTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-24 | — | — | US | disclosed |
| EP-0218118-A1 | Arylmethyl azoles and their salts, method for their preparation, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-15 | — | — | EP | disclosed |