Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GRM6 | O15303 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.56 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.56 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.56 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.56 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.56 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.56 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746936 | 0.86 | KDM4E (0.45) | KMT2AKDM4EMEN1GRM6ALDH1A1 | |
| SCHEMBL9747505 | 0.79 | MAPT (0.48) | KMT2AKDM4EMEN1GRM6ALDH1A1 | |
| SCHEMBL3683483 | 0.78 | KMT2A (0.67) | KMT2AKDM4EMEN1GRM6ALDH1A1 | |
| SCHEMBL8609148 | 0.77 | PARP1 (0.53) | KMT2AKDM4EMEN1GRM6ALDH1A1 | |
| SCHEMBL9747110 | 0.76 | MAPT (0.42) | KMT2AKDM4EMEN1GRM6ALDH1A1 | |
| SCHEMBL9138970 | 0.75 | CDK2 (0.78) | HSD17B10TDP1CDK2CA2CA1 | |
| SCHEMBL31387051 | 0.73 | PARP1 (0.58) | KMT2AKDM4EALDH1A1HPGDRECQL | |
| Nbqx SCHEMBL120375 | 0.73 | GRIA1 (1.00) | KMT2AKDM4EMEN1GRM6ALDH1A1 | |
| Nbqx SCHEMBL29356960 | 0.73 | GRIA1 (1.00) | KMT2AKDM4EMEN1GRM6ALDH1A1 | |
| Nbqx SCHEMBL2487669 | 0.72 | GRIA1 (0.98) | KMT2AKDM4EMEN1GRM6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858560-B2 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | CAPROTEC BIOANALYTICS GMBH (DE) | 2010-12-28 | — | — | US | disclosed |
| EP-0511152-A2 | Quinoxaline compounds, their preparation and use | NOVO NORDISK A/S (DK) | 1992-10-28 | — | — | EP | disclosed |