Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GRM6 | O15303 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.48 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.48 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.48 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9747279 | 0.79 | MAPT (0.49) | MAPTCYP2C19TDP1KDM4EALDH1A1 | |
| SCHEMBL9747625 | 0.79 | KMT2A (0.56) | MAPTCYP2C19TDP1KDM4EALDH1A1 | |
| SCHEMBL9747632 | 0.78 | LMNA (0.45) | MAPTCYP2C19TDP1KDM4EALDH1A1 | |
| SCHEMBL3682051 | 0.75 | MAPT (0.62) | MAPTCYP2C19TDP1KDM4EALDH1A1 | |
| SCHEMBL3670356 | 0.75 | GRIA1 (0.72) | MAPTCYP2C19TDP1KDM4EALDH1A1 | |
| SCHEMBL3683241 | 0.73 | MAPT (0.45) | MAPTCYP2C19TDP1KDM4EALDH1A1 | |
| SCHEMBL9747794 | 0.72 | GRIN2D (0.45) | MAPTCYP2C19TDP1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL3683097 | 0.72 | MAPT (0.44) | MAPTCYP2C19TDP1KDM4EALDH1A1 | |
| SCHEMBL3687754 | 0.72 | MAPT (0.62) | MAPTCYP2C19TDP1KDM4EALDH1A1 | |
| SCHEMBL9747110 | 0.71 | MAPT (0.42) | MAPTCYP2C19TDP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511152-A2 | Quinoxaline compounds, their preparation and use | NOVO NORDISK A/S (DK) | 1992-10-28 | — | — | EP | disclosed |