Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27455362 | 0.83 | CYP2D6 (0.59) | TSHRALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL203311 | 0.82 | TSHR (0.53) | TSHRALDH1A1L3MBTL1TDP1CYP3A4 | |
| SCHEMBL20578201 | 0.82 | CYP1A2 (0.54) | TSHRALDH1A1L3MBTL1TDP1CYP3A4 | |
| SCHEMBL1665613 | 0.80 | TSHR (0.55) | TSHRALDH1A1L3MBTL1TDP1CYP3A4 | |
| SCHEMBL28767920 | 0.80 | ALDH1A1 (0.55) | TSHRALDH1A1L3MBTL1TDP1CYP3A4 | |
| SCHEMBL28203253 | 0.80 | CLCN2 (0.38) | TSHRCYP1A2CYP2D6CYP2C19CA2 | |
| SCHEMBL3286890 | 0.79 | TSHR (0.48) | TSHRALDH1A1L3MBTL1TDP1CYP3A4 | |
| SCHEMBL109178 | 0.77 | TSHR (0.50) | TSHRALDH1A1L3MBTL1TDP1CYP3A4 | |
| SCHEMBL30111657 | 0.77 | TSHR (0.50) | TSHRALDH1A1L3MBTL1TDP1CYP3A4 | |
| SCHEMBL20578202 | 0.77 | CYP2D6 (0.53) | TSHRALDH1A1L3MBTL1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497896-A1 | NON-PHOTOGRAPHIC METHOD FOR PATTERNING ORGANIC POLYMER FILMS. | DU PONT (US) | 1992-08-12 | — | — | EP | disclosed |
| US-5032216-A | Non-photographic method for patterning organic polymer films | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-07-16 | — | — | US | disclosed |
| WO-1991006118-A1 | NON-PHOTOGRAPHIC METHOD FOR PATTERNING ORGANIC POLYMER FILMS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-05-02 | — | — | WO | disclosed |