Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.34 |
| ▸ | ESR1 | P03372 | 5/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | ESRRB | O95718 | 1/20 | 0.33 |
| ▸ | ESRRA | P11474 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2962921 | 0.87 | STS (0.47) | STSHRH3ESR1ESR2ESRRB | |
| SCHEMBL27339223 | 0.82 | AR (0.47) | STSESR1ESR2ESRRBESRRA | |
| SCHEMBL5897640 | 0.78 | ESR1 (0.50) | STSESR1ESR2ESRRBESRRA | |
| SCHEMBL6467608 | 0.78 | ESR1 (0.50) | STSESR1ESR2ESRRBESRRA | |
| SCHEMBL5270945 | 0.75 | STS (0.38) | STSHRH3ESR1HDAC3HDAC6 | |
| SCHEMBL6462357 | 0.72 | STS (0.54) | STSHRH3ESR1ESR2 | |
| SCHEMBL11776204 | 0.71 | ESR1 (0.65) | STSESR1ESR2ESRRBESRRA | |
| SCHEMBL25863903 | 0.69 | ESR1 (0.49) | STSHRH3ESR1ESR2ESRRB | |
| SCHEMBL25863838 | 0.69 | ESR1 (0.49) | STSHRH3ESR1ESR2ESRRB | |
| SCHEMBL25863906 | 0.69 | ESR1 (0.49) | STSHRH3ESR1ESR2ESRRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34136-E | Morning-after contraceptives | SRI INTERNATIONAL (US) | 1992-12-01 | — | — | US | disclosed |
| US-4859370-A | 9 alpha, 11 beta-substituted and 11 beta-substituted estranes | SRI INTERNATIONAL (US) | 1989-08-22 | — | — | US | disclosed |
| US-4705783-A | 9α, 11β-substituted and 11β-substituted estranes | SRI INTERNATIONAL (US) | 1987-11-10 | — | — | US | disclosed |
| WO-1987000175-A1 | 9alpha, 11beta-SUBSTITUTED AND 11beta-SUBSTITUTED ESTRANES | SRI INTERNATIONAL (US) | 1987-01-15 | — | — | WO | disclosed |