⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2307987 | 0.89 | LMNA (0.43) | — | |
| SCHEMBL302184 | 0.89 | — | — | |
| SCHEMBL75 | 0.89 | — | — | |
| SCHEMBL1268609 | 0.80 | — | — | |
| SCHEMBL21708061 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL560437 | 0.80 | — | — | |
| SCHEMBL11790114 | 0.80 | — | — | |
| SCHEMBL20815413 | 0.80 | — | — | |
| SCHEMBL1099969 | 0.80 | — | — | |
| SCHEMBL20815426 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215250-B1 | 2-SUBSTITUTED-1,4-DIHYDROPYRIDINES, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-12-30 | — | — | EP | disclosed |
| EP-0215250-A1 | 2-Substituted-1,4-dihydropyridines, method for their preparation and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1987-03-25 | — | — | EP | disclosed |