Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 8/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27876632 | 0.84 | ATM (0.50) | MAPTCACNA1BAPBA1HCAR2ATM | |
| SCHEMBL2781020 | 0.80 | HCAR2 (0.64) | MAPTHCAR2ATMRAB9ANPSR1 | |
| SCHEMBL1326208 | 0.80 | HCAR2 (0.64) | MAPTHCAR2ATMRAB9ANPSR1 | |
| SCHEMBL1326211 | 0.80 | HCAR2 (0.64) | MAPTHCAR2ATMRAB9ANPSR1 | |
| SCHEMBL10672946 | 0.78 | TSHR (0.52) | MAPTCACNA1BAPBA1HCAR2ATM | |
| SCHEMBL11459654 | 0.78 | ATM (0.56) | MAPTCACNA1BAPBA1HCAR2ATM | |
| SCHEMBL24045655 | 0.77 | HCAR2 (0.54) | MAPTCACNA1BAPBA1HCAR2ATM | |
| SCHEMBL3677660 | 0.77 | HCAR2 (0.67) | MAPTCACNA1BAPBA1HCAR2ATM | |
| SCHEMBL250270 | 0.77 | MAPT (0.69) | MAPTCACNA1BAPBA1HCAR2ATM | |
| SCHEMBL5873269 | 0.76 | HCAR2 (0.65) | MAPTHCAR2ATMNPSR1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112989-A | Process for producing unsaturated mono and dicarboxylic acid imide compound | MATSUSHITA ELECTRIC WORKS LTD. (JP) | 1992-05-12 | — | — | US | disclosed |