SCHEMBL9747825

SCHEMBL9747825

CN[Si](C1CCCCC1)(C1CCCCC1)C1CCCCC1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29641357 0.81 ALDH1A1 (0.35) ALDH1A1HSD17B10
SCHEMBL232504 0.77 ALDH1A1 (0.32) ALDH1A1HSD17B10
SCHEMBL234184 0.77 ALDH1A1 (0.32) ALDH1A1HSD17B10
SCHEMBL235765 0.77 ALDH1A1 (0.32) ALDH1A1HSD17B10
SCHEMBL231661 0.74 ALDH1A1 (0.30) ALDH1A1HSD17B10
SCHEMBL233763 0.73
SCHEMBL232326 0.73
SCHEMBL27966791 0.72
SCHEMBL234045 0.71
SCHEMBL28812671 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104066509-B Moisture-curable organopolysiloxane composition 莫门蒂夫性能材料股份有限公司 2016-12-21 CN claimed
CN-104066509-A Moisture-curable organopolysiloxane composition MOMENTIVE PERFORMANCE MAT INC 2014-09-24 CN claimed
CN-107429079-B Curable resin composition surface treatment pearl filler and the curable resin composition containing the filler 丸尾钙株式会社 2019-08-23 CN disclosed
CN-105229091-B Anti-fouling system comprising silicone-hydrogel 莫门蒂夫性能材料股份有限公司 2019-03-08 CN disclosed
CN-105358606-B The organopolysiloxane composition of nonmetal catalyzed room temperature moisture-curable 莫门蒂夫性能材料股份有限公司 2018-02-16 CN disclosed
CN-105121155-B Anti-fouling system comprising silicone-hydrogel 莫门蒂夫性能材料股份有限公司 2018-01-26 CN disclosed
CN-107429079-A Curable resin composition surface treatment pearl filler and the curable resin composition containing the filler 丸尾钙株式会社 2017-12-01 CN disclosed
CN-107075063-A The composition of moisture-curable 莫门蒂夫性能材料股份有限公司 2017-08-18 CN disclosed
CN-104395405-B Moisture-curing organopolysiloxane composition 莫门蒂夫性能材料股份有限公司 2017-04-26 CN disclosed
CN-104114598-B Moisture-curing organopolysiloxane composition 莫门蒂夫性能材料股份有限公司 2017-03-01 CN disclosed
CN-104066509-B Moisture-curable organopolysiloxane composition 莫门蒂夫性能材料股份有限公司 2016-12-21 CN disclosed
CN-105121155-A Antifouling system comprising silicone hydrogel MOMENTIVE PERFORMANCE MAT INC 2015-12-02 CN disclosed
CN-104066509-A Moisture-curable organopolysiloxane composition MOMENTIVE PERFORMANCE MAT INC 2014-09-24 CN disclosed
CN-1282353-A A polysiloxane having copolymer dispersed therein and sealants containing the same GOODRICH CO B F (US) 2001-01-31 CN disclosed
EP-0321524-B1 PHARMACEUTICAL FORMULATION ENSURING THE TRANSDERMAL ABSORPTION OF THE ACTIVE INGREDIENT AND PROCESS FOR PREPARING SAME BIOGAL GYOGYSZERGYAR (HU) 1992-10-21 EP disclosed
US-4997655-A Polysiloxanes BIOGAL GYOGYSZERGYAR (HU) 1991-03-05 US disclosed
EP-0321524-A1 PHARMACEUTICAL FORMULATION ENSURING THE TRANSDERMAL ABSORPTION OF THE ACTIVE INGREDIENT AND PROCESS FOR PREPARING SAME. BIOGAL GYOGYSZERGYAR (HU) 1989-06-28 EP disclosed
CN-1031324-A Guarantee pharmaceutical preparation that the active component percutaneous absorbs and preparation method thereof BIOGAL GYOGYSZERGYAR (HU) 1989-03-01 CN disclosed
WO-1988010111-A1 PHARMACEUTICAL FORMULATION ENSURING THE TRANSDERMAL ABSORPTION OF THE ACTIVE INGREDIENT AND PROCESS FOR PREPARING SAME BIOGAL Gyógyszergyár (HU) 1988-12-29 WO disclosed