Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.64 |
| ▸ | NPC1 | O15118 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1746713 | 0.81 | TSHR (0.71) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL10872912 | 0.79 | NPC1 (0.62) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL11188532 | 0.78 | MAPT (1.00) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL13680524 | 0.76 | MAPT (0.58) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL10692209 | 0.75 | NPC1 (0.60) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL23385399 | 0.75 | MAPK1 (0.54) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL14439016 | 0.74 | CYP1A2 (0.62) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL25389377 | 0.73 | CHRM5 (0.62) | RAB9ASMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL25464930 | 0.72 | LOXL2 (0.63) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL6580556 | 0.72 | LOXL2 (0.63) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |