Alteconazole

Alteconazole

SCHEMBL9748291

Clc1ccc(C2(Cn3cncn3)OC2c2ccc(Cl)cc2Cl)cc1

nearest known ligand 0.49

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 7/20 0.49
THRB P10828 2/20 0.49
CYP2C9 P11712 3/20 0.47
CYP1A2 P05177 2/20 0.42
CYP2D6 P10635 2/20 0.42
CYP2C19 P33261 2/20 0.42
KDM4E B2RXH2 2/20 0.42
SLC6A2 P23975 2/20 0.40
SLC6A4 P31645 2/20 0.40
SLC6A3 Q01959 2/20 0.40
CYP19A1 P11511 1/20 0.39
LMNA P02545 2/20 0.39
HTT P42858 2/20 0.39
NR1I2 O75469 1/20 0.39
FYN P06241 1/20 0.39
PGR P06401 1/20 0.39
HSP90AA1 P07900 1/20 0.39
CHRM2 P08172 1/20 0.39
CHRM4 P08173 1/20 0.39
CHRM5 P08912 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alteconazole SCHEMBL2110163 1.00 CYP3A4 (0.49) CYP3A4THRBCYP2C9CYP1A2CYP2D6
Alteconazole SCHEMBL30416434 1.00 CYP3A4 (0.49) CYP3A4THRBCYP2C9CYP1A2CYP2D6
SCHEMBL10844736 0.90 CYP3A4 (0.46) CYP3A4THRBCYP2C9CYP1A2CYP2D6
SCHEMBL10425812 0.88 CYP3A4 (0.43) CYP3A4THRBCYP2C9CYP1A2CYP2D6
SCHEMBL10843665 0.88 CYP3A4 (0.48) CYP3A4THRBCYP2C9CYP1A2CYP2D6
SCHEMBL9834697 0.87 CYP3A4 (0.43) CYP3A4THRBCYP2C9CYP1A2CYP2D6
SCHEMBL10845394 0.87 CYP3A4 (0.43) CYP3A4THRBCYP2C9CYP1A2CYP2D6
SCHEMBL3467654 0.86 CYP3A4 (0.48) CYP3A4THRBCYP2C9CYP1A2CYP2D6
SCHEMBL2557411 0.86 CYP3A4 (0.48) CYP3A4THRBCYP2C9CYP1A2CYP2D6
SCHEMBL9668373 0.81 GAA (0.44) CYP3A4THRBCYP2C9CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0196038-B1 AZOLYL METHYL OXIRANES, THEIR PREPARATION AND USE AS PLANT-PROTECTING AGENTS BASF Aktiengesellschaft (DE) 1992-01-02 EP disclosed
US-4906652-A Azolymethyloxiranes and their use as crop protection agents BASF AKTIENGESELLSCHAFT (DE) 1990-03-06 US disclosed
EP-0094564-B1 AZOLYL-METHYL OXIRANES, THEIR PREPARATION AND USE AS MEDICAMENTS AND PLANT PROTECTING AGENTS BASF Aktiengesellschaft (DE) 1987-09-30 EP disclosed
EP-0196038-A2 Azolyl methyl oxiranes, their preparation and use as plant-protecting agents BASF Aktiengesellschaft (DE) 1986-10-01 EP disclosed
US-4464381-A Fungicides containing azolylmethyloxiranes BASF AKTIENGESELLSCHAFT (DE) 1984-08-07 US disclosed
EP-0094564-A2 Azolyl-methyl oxiranes, their preparation and use as medicaments and plant protecting agents BASF Aktiengesellschaft (DE) 1983-11-23 EP disclosed