Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tetramethylammonium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetramethylammonium Ion SCHEMBL108419 | 0.95 | — | — | |
| Tetramethylammonium Ion SCHEMBL29047744 | 0.95 | CA1 (0.56) | CA1CA2CA9FFAR3LCK | |
| Tetramethylammonium Ion SCHEMBL28181200 | 0.91 | CA1 (0.42) | CA1CA2CA9FFAR3LCK | |
| Tetramethylammonium Ion SCHEMBL28607019 | 0.90 | CA1 (0.50) | CA1CA2CA9FFAR3LCK | |
| Tetramethylammonium Ion SCHEMBL6113743 | 0.90 | — | — | |
| Tetramethylammonium Ion SCHEMBL9748322 | 0.88 | CA1 (0.40) | CA1CA2CA9FFAR3LCK | |
| Tetramethylammonium Ion SCHEMBL9748331 | 0.88 | CA1 (0.40) | CA1CA2CA9FFAR3LCK | |
| Tetramethylammonium Ion SCHEMBL20377497 | 0.86 | FFAR3 (0.64) | CA1CA2CA9FFAR3LCK | |
| Tetramethylammonium Ion SCHEMBL28099301 | 0.86 | CA1 (0.46) | CA1CA2CA9FFAR3LCK | |
| Tetramethylammonium Ion SCHEMBL28103347 | 0.86 | CA1 (0.46) | CA1CA2CA9FFAR3LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149682-A | Stirring the mixed solution, slurrying, precipitation, recovering, drying | W. R. GRACE & CO. -CONN. (US) | 1992-09-22 | — | — | US | claimed |