Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tetramethylammonium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetramethylammonium Ion SCHEMBL28103347 | 0.91 | CA1 (0.46) | CA1CA2CA9TSHRFFAR3 | |
| Tetramethylammonium Ion SCHEMBL108419 | 0.91 | — | — | |
| Tetramethylammonium Ion SCHEMBL29047744 | 0.91 | CA1 (0.56) | CA1CA2CA9TSHRFFAR3 | |
| Tetramethylammonium Ion SCHEMBL28607019 | 0.86 | CA1 (0.50) | CA1CA2CA9TSHRFFAR3 | |
| Tetramethylammonium Ion SCHEMBL9748327 | 0.86 | CA1 (0.50) | CA1CA2CA9TSHRFFAR3 | |
| Tetramethylammonium Ion SCHEMBL6113743 | 0.86 | — | — | |
| Tetramethylammonium Ion SCHEMBL28135669 | 0.82 | CA1 (0.46) | CA1CA2CA9TSHRFFAR3 | |
| Bicarbonate SCHEMBL4527467 | 0.80 | — | — | |
| Bicarbonate SCHEMBL27903356 | 0.80 | — | — | |
| Bicarbonate SCHEMBL4527463 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107267117-B | Liquid crystal sealing agent composition, curable resin and (methyl) acrylated curable resin | 协立化学产业株式会社 | 2019-11-05 | — | — | CN | disclosed |
| CN-107267117-A | Liquid crystal sealing agent composition, curable resin and (methyl) acrylated curable resin | 协立化学产业株式会社 | 2017-10-20 | — | — | CN | disclosed |
| CN-105934459-B | Curable resin having excellent flexibility after curing, (meth) acryloyl curable resin, and liquid crystal sealing composition | 协立化学产业株式会社 | 2017-06-16 | — | — | CN | disclosed |
| CN-105934459-A | Curable resin having excellent flexibility after curing, (meth) acryloyl curable resin, and liquid crystal sealing composition | 协立化学产业株式会社 | 2016-09-07 | — | — | CN | disclosed |