Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.63 |
| ▸ | ACHE | P22303 | 8/20 | 0.63 |
| ▸ | BCHE | P06276 | 8/20 | 0.62 |
| ▸ | APP | P05067 | 2/20 | 0.62 |
| ▸ | BACE1 | P56817 | 2/20 | 0.62 |
| ▸ | GABRP | O00591 | 1/20 | 0.62 |
| ▸ | GABRD | O14764 | 1/20 | 0.62 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.62 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.62 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.62 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.62 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.62 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.62 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.62 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.62 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.62 |
| ▸ | GABRE | P78334 | 1/20 | 0.62 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.62 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.62 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29522722 | 0.84 | ACHE (0.66) | ACHEBCHEAPPBACE1GABRP | |
| SCHEMBL16684277 | 0.84 | ACHE (0.66) | ACHEBCHEAPPBACE1GABRP | |
| SCHEMBL22930959 | 0.83 | CACNA2D1 (0.62) | CACNA2D1ACHEBCHEAPPBACE1 | |
| SCHEMBL22930960 | 0.81 | CACNA2D1 (0.54) | CACNA2D1ACHEBCHEAPPBACE1 | |
| SCHEMBL7945036 | 0.81 | BCHE (0.65) | ACHEBCHEAPPBACE1GABRP | |
| SCHEMBL22930961 | 0.81 | BCHE (0.72) | ACHEBCHEAPPBACE1GABRP | |
| SCHEMBL12552069 | 0.81 | ACHE (0.73) | ACHEBCHEAPPBACE1GABRP | |
| SCHEMBL7941639 | 0.81 | ACHE (0.61) | ACHEBCHEAPPBACE1GABRP | |
| SCHEMBL17124047 | 0.81 | ACHE (0.61) | ACHEBCHEAPPBACE1GABRP | |
| SCHEMBL14232862 | 0.80 | ACHE (0.66) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175172-A | Administering amino-1,2,3,4-tetrahydroacridine and derivatives for elevation of T4 lymphocytes level in patients | DIETLIN FRANCOIS (FR) | 1992-12-29 | — | — | US | disclosed |