SCHEMBL9748619

SCHEMBL9748619

CC1(C)Cc2ccc(OCc3ccccc3)cc2O1

nearest known ligand 0.69

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOB P27338 13/20 0.69
MAOA P21397 2/20 0.54
CA2 P00918 1/20 0.51
CA5A P35218 1/20 0.51
HIF1A Q16665 3/20 0.51
HRH3 Q9Y5N1 1/20 0.50
NPC1 O15118 1/20 0.50
ALDH1A1 P00352 1/20 0.50
MAPT P10636 1/20 0.50
RAB9A P51151 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4726898 0.82 MAOB (1.00) MAOBMAOANPC1ALDH1A1MAPT
SCHEMBL21326806 0.81 MAOB (0.51) MAOBMAOACA2CA5AHIF1A
SCHEMBL6604268 0.79 MAOB (0.82) MAOBNPC1ALDH1A1MAPTRAB9A
SCHEMBL10425924 0.78 MAOB (0.46) MAOBMAOANPC1ALDH1A1MAPT
SCHEMBL27498274 0.78 MAOB (0.56) MAOBMAOACA2CA5AHRH3
SCHEMBL21741652 0.78 MAOB (0.48) MAOBMAOACA2CA5AHIF1A
SCHEMBL21326784 0.77 CA2 (0.48) MAOBMAOACA2CA5AHIF1A
SCHEMBL21326813 0.77 MAOB (0.49) MAOBMAOACA2CA5AHIF1A
SCHEMBL6603113 0.76 MAOB (0.60) MAOBMAOANPC1ALDH1A1MAPT
SCHEMBL6603109 0.76 MAOB (0.60) MAOBMAOANPC1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012049555-A1 SPIROCYCLIC COMPOUNDS AS VOLTAGE-GATED SODIUM CHANNEL MODULATORS LUPIN LIMITED (IN) 2012-04-19 WO disclosed
EP-0230475-B1 NOVEL UREA DERIVATIVES, PROCESSES FOR PRODUCTION THEREOF AND HERBICIDE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-03-18 EP disclosed
US-4838924-A NONPHYTOTOXIC MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-06-13 US disclosed