Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26B1 | Q9NR63 | 8/20 | 0.57 |
| ▸ | CYP26A1 | O43174 | 8/20 | 0.57 |
| ▸ | RARA | P10276 | 8/20 | 0.53 |
| ▸ | RARB | P10826 | 8/20 | 0.53 |
| ▸ | RARG | P13631 | 8/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | RXRA | P19793 | 3/20 | 0.47 |
| ▸ | RXRB | P28702 | 3/20 | 0.47 |
| ▸ | RXRG | P48443 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746403 | 0.83 | RARB (0.75) | CYP26B1CYP26A1RARARARBRARG | |
| SCHEMBL5712126 | 0.83 | RARB (0.75) | CYP26B1CYP26A1RARARARBRARG | |
| SCHEMBL5712098 | 0.83 | RARB (0.75) | CYP26B1CYP26A1RARARARBRARG | |
| SCHEMBL21776768 | 0.80 | CYP26B1 (0.83) | CYP26B1CYP26A1RARARARBRARG | |
| SCHEMBL29605538 | 0.80 | CYP26B1 (0.83) | CYP26B1CYP26A1RARARARBRARG | |
| SCHEMBL10541851 | 0.80 | RARB (0.58) | CYP26B1CYP26A1RARARARBRARG | |
| SCHEMBL16516895 | 0.78 | CYP26B1 (0.71) | CYP26B1CYP26A1RARARARBRARG | |
| SCHEMBL9746770 | 0.77 | RARA (0.52) | CYP26B1CYP26A1RARARARBRARG | |
| SCHEMBL9746767 | 0.77 | RARA (0.52) | CYP26B1CYP26A1RARARARBRARG | |
| SCHEMBL9746761 | 0.77 | RARB (0.53) | CYP26B1CYP26A1RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220118-B1 | BICYCLIC NAPHTHALENIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1992-01-02 | — | — | EP | claimed |