Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6758128 | 0.91 | PTPN22 (0.43) | MAPTKDM4EALOX12PTPN22ALDH1A1 | |
| SCHEMBL5404231 | 0.84 | KDM1A (0.43) | MAPTALDH1A1NPSR1CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL6384484 | 0.84 | KDM1A (0.35) | MAPTKDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL16398217 | 0.80 | KDM1A (0.42) | MAPTALDH1A1NPSR1CYP2C9CYP2C19 | |
| SCHEMBL16398218 | 0.80 | KDM1A (0.42) | MAPTALDH1A1NPSR1CYP2C9CYP2C19 | |
| SCHEMBL17747353 | 0.78 | KDM1A (0.41) | MAPTKDM4EALDH1A1NPSR1HSD17B10 | |
| SCHEMBL17747355 | 0.78 | KDM1A (0.41) | MAPTKDM4EALDH1A1NPSR1HSD17B10 | |
| SCHEMBL17747357 | 0.78 | KDM1A (0.41) | MAPTKDM4EALDH1A1NPSR1HSD17B10 | |
| SCHEMBL11003369 | 0.74 | PTPN22 (0.48) | MAPTKDM4EALOX12PTPN22ALDH1A1 | |
| SCHEMBL30631565 | 0.74 | MEN1 (0.43) | MAPTKDM4EALOX12ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101624332-B | Novel compound with antitumor activity and application thereof | GUANZHOU INST OF BIOMEDICINE AND HEALTH CHINESE ACADEMY OF SCIENCE | 2012-11-21 | — | — | CN | claimed |
| CN-101624332-A | Novel compound with antitumor activity and application thereof | GUANZHOU INST OF BIOMEDICINE A | 2010-01-13 | — | — | CN | claimed |
| CN-101624332-B | Novel compound with antitumor activity and application thereof | GUANZHOU INST OF BIOMEDICINE AND HEALTH CHINESE ACADEMY OF SCIENCE | 2012-11-21 | — | — | CN | disclosed |
| CN-101624332-A | Novel compound with antitumor activity and application thereof | GUANZHOU INST OF BIOMEDICINE A | 2010-01-13 | — | — | CN | disclosed |
| EP-0201071-B1 | 2-SUBSTITUTED-1-NAPHTHOLS AS 5-LIPOXYGENASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-03-04 | — | — | EP | disclosed |
| US-5026759-A | Antiinflammatory agents respiratory system disorders | DU PONT MERCK PHARMACEUTICAL (US) | 1991-06-25 | — | — | US | disclosed |
| US-4985442-A | ANTIINFLAMMATORY, LUNG DISEASES, PSORIASIS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| US-4985435-A | TREATMENT OF INFLAMMATION, OBSTRUCTIVE LUNG DISEASES AND PSORIASIS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| US-4906636-A | 2-Substituted-1-naphthols as 5-lipoxygenase inhibitors | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-06 | — | — | US | disclosed |
| US-4833164-A | ANTIINFLAMMATORY AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-05-23 | — | — | US | disclosed |
| EP-0201071-A2 | 2-Substituted-1-naphthols as 5-lipoxygenase inhibitors | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1986-11-12 | — | — | EP | disclosed |