Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.50 |
| ▸ | TACR3 | P29371 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15093398 | 0.89 | POLB (0.56) | HSD17B10ALDH1A1TACR3POLB | |
| SCHEMBL15093708 | 0.84 | TACR3 (0.53) | ALDH1A1TACR3POLB | |
| SCHEMBL8709321 | 0.84 | HSD17B10 (0.63) | HSD17B10EPHX1ALDH1A1ROCK2ROCK1 | |
| SCHEMBL10649583 | 0.84 | HSD17B10 (0.49) | HSD17B10EPHX1ALDH1A1HTTROCK2 | |
| SCHEMBL15093655 | 0.83 | TACR3 (0.55) | ALDH1A1TACR3POLB | |
| SCHEMBL15093823 | 0.83 | TACR3 (0.55) | ALDH1A1TACR3POLB | |
| SCHEMBL15093649 | 0.83 | TACR3 (0.55) | ALDH1A1TACR3POLB | |
| SCHEMBL15093938 | 0.83 | TACR3 (0.55) | ALDH1A1TACR3POLB | |
| Bromide SCHEMBL10650557 | 0.83 | HSD17B10 (0.48) | HSD17B10EPHX1ALDH1A1HTTROCK2 | |
| SCHEMBL894067 | 0.83 | POLB (0.56) | HSD17B10ALDH1A1TACR3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126483-A | Anticholesterol and antilipemic agents | MITSUBISHI KASEI CORPORATION (JP) | 1992-06-30 | — | — | US | disclosed |