Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10650557 | 0.99 | HSD17B10 (0.48) | HSD17B10EPHX1ALDH1A1HTTCNR2 | |
| SCHEMBL9749085 | 0.84 | HSD17B10 (0.56) | HSD17B10EPHX1ALDH1A1HTTMEN1 | |
| SCHEMBL10648073 | 0.77 | ITGB3 (0.47) | EPHX1ALDH1A1HTTMEN1KMT2A | |
| Bromide SCHEMBL10649465 | 0.77 | GAA (0.54) | HSD17B10EPHX1CNR2MEN1KMT2A | |
| SCHEMBL11585568 | 0.76 | HSD17B10 (0.55) | HSD17B10EPHX1ALDH1A1HTTMEN1 | |
| Bromide SCHEMBL10647943 | 0.75 | HSD17B10 (0.50) | HSD17B10EPHX1ALDH1A1HTTCNR2 | |
| SCHEMBL8709321 | 0.75 | HSD17B10 (0.63) | HSD17B10EPHX1ALDH1A1SMN1; SMN2ROCK2 | |
| SCHEMBL10648220 | 0.75 | CNR2 (0.51) | EPHX1ALDH1A1HTTCNR2MEN1 | |
| SCHEMBL10596369 | 0.74 | ENPP2 (0.59) | HSD17B10EPHX1ALDH1A1HTTMEN1 | |
| SCHEMBL6379798 | 0.74 | FPR2 (0.63) | HSD17B10EPHX1ALDH1A1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4752621-A | Arylalkyl amines useful for lowering intraocular pressure | SYNTEX (U.S.A.) INC. (US) | 1988-06-21 | — | — | US | claimed |