Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | JAK2 | O60674 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.56 |
| ▸ | ICMT | O60725 | 3/20 | 0.56 |
| ▸ | ALB | P02768 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11506385 | 0.98 | MEN1 (0.68) | MEN1KMT2AUSP2HSD17B10NPC1 | |
| SCHEMBL9339208 | 0.84 | NPC1 (0.61) | MEN1KMT2ANPC1JAK2RAB9A | |
| SCHEMBL31310431 | 0.83 | NPC1 (0.64) | MEN1KMT2ANPC1JAK2RAB9A | |
| SCHEMBL25227336 | 0.83 | NPC1 (0.60) | MEN1KMT2ANPC1JAK2RAB9A | |
| SCHEMBL9339113 | 0.83 | NPC1 (0.64) | MEN1KMT2ANPC1JAK2RAB9A | |
| SCHEMBL10596306 | 0.83 | CA12 (0.61) | MEN1KMT2AHDAC6ICMTALB | |
| SCHEMBL4304223 | 0.82 | MEN1 (1.00) | MEN1KMT2AUSP2HSD17B10NPC1 | |
| SCHEMBL28666105 | 0.82 | NPC1 (0.62) | NPC1JAK2RAB9APAX8HDAC6 | |
| SCHEMBL25277657 | 0.82 | NPC1 (0.62) | MEN1KMT2ANPC1JAK2RAB9A | |
| SCHEMBL13952345 | 0.81 | ICMT (0.58) | MEN1KMT2AHDAC6ICMTALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126483-A | Anticholesterol and antilipemic agents | MITSUBISHI KASEI CORPORATION (JP) | 1992-06-30 | — | — | US | disclosed |