Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CCR8 | P51685 | 1/20 | 0.45 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18396791 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2APKMNPSR1 | |
| SCHEMBL31432992 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2APKMNPSR1 | |
| SCHEMBL18397552 | 0.96 | MEN1 (0.46) | ALDH1A1MEN1KMT2APKMNPSR1 | |
| SCHEMBL11106021 | 0.91 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2APKMNPSR1 | |
| SCHEMBL9083343 | 0.91 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2APKMNPSR1 | |
| SCHEMBL10258854 | 0.91 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2APKMNPSR1 | |
| SCHEMBL14754192 | 0.91 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2APKMNPSR1 | |
| SCHEMBL3718243 | 0.91 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2APKMNPSR1 | |
| SCHEMBL5466112 | 0.91 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2APKMNPSR1 | |
| Hydrochloric Acid SCHEMBL29999389 | 0.90 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2APKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999239-B | Method for synthesizing diaza-bridge compound | 上海凌富药物研究有限公司 | 2022-11-11 | — | — | CN | disclosed |
| EP-3932917-A2 | SUBSTITUTED PHENYLOXAZOLIDINONES FOR ANTIMICROBIAL THERAPY | The Global Alliance for TB Drug Development, Inc. (US) | 2022-01-05 | — | — | EP | disclosed |
| EP-3307268-A1 | SUBSTITUTED PHENYLOXAZOLIDINONES FOR ANTIMICROBIAL THERAPY | The Global Alliance for TB Drug Development Inc. (US) | 2018-04-18 | — | — | EP | disclosed |
| WO-2017015106-A1 | SUBSTITUTED PHENYLOXAZOLIDINONES FOR ANTIMICROBIAL THERAPY | THE GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT, INC. (US) | 2017-01-26 | — | — | WO | disclosed |
| US-5091383-A | SUBSTITUTED BRIDGED DIAZABICYCLOALKYL QUINOLONE CARBOXYLIC ACIDS | PFIZER INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0215650-B1 | SUBSTITUTED BRIDGED-DIAZABICYCLOALKYL QUINOLONE CARBOXYLIC ACIDS | PFIZER INC. (US) | 1992-01-29 | — | — | EP | disclosed |
| US-4861779-A | Anti-bacterial substituted bridged-diazabicycloalkyl quinolone carboxylic acids | PFIZER INC. (US) | 1989-08-29 | — | — | US | disclosed |
| US-4775668-A | Substituted bridged-diazabicycloalkyl quinolone carboxylic acids and anti-bacterial use thereof | PFIZER INC. (US) | 1988-10-04 | — | — | US | disclosed |
| EP-0215650-A2 | Substituted bridged-diazabicycloalkyl quinolone carboxylic acids | PFIZER INC. (US) | 1987-03-25 | — | — | EP | disclosed |