Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 8/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | INSR | P06213 | 1/20 | 0.35 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | CASP9 | P55211 | 1/20 | 0.35 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8449025 | 0.86 | CYP2C9 (0.41) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL8449020 | 0.86 | CYP2C9 (0.41) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL4803851 | 0.85 | CYP2C9 (0.50) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL4803860 | 0.85 | CYP2C9 (0.50) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL11064481 | 0.84 | CYP2C9 (0.40) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL11064485 | 0.84 | CYP2C9 (0.40) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL2014945 | 0.84 | CYP2C9 (0.48) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL2014941 | 0.84 | CYP2C9 (0.48) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL11191523 | 0.83 | SPHK1 (0.50) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL11190738 | 0.83 | SPHK1 (0.50) | CYP2C9MAPTALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220463-B1 | POLYMER MATERIALS PRESENTING A LIQUID CRYSTAL PHASE | MERCK PATENT GmbH (DE) | 1992-01-02 | — | — | EP | disclosed |
| EP-0220463-A2 | Polymer materials presenting a liquid crystal phase | MERCK PATENT GmbH (DE) | 1987-05-06 | — | — | EP | disclosed |