SCHEMBL2014945

SCHEMBL2014945

CCCCCC1CCC(c2ccc(-c3ccc(N)cc3)cc2)CC1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.48
MAPT P10636 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
MAPK1 P28482 1/20 0.46
SPHK1 Q9NYA1 9/20 0.46
GAA P10253 1/20 0.41
ESR2 Q92731 1/20 0.41
CYP19A1 P11511 1/20 0.38
DGAT1 O75907 1/20 0.38
SOAT1 P35610 1/20 0.38
SPHK2 Q9NRA0 5/20 0.37
GRM2 Q14416 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2014941 1.00 CYP2C9 (0.48) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL7752413 0.95 CYP2C9 (0.51) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL11117357 0.95 CYP2C9 (0.51) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL7752594 0.94 SPHK1 (0.51) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL7747175 0.94 SPHK1 (0.51) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL7751373 0.94 SPHK1 (0.51) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL10781226 0.94 SPHK1 (0.51) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL7747021 0.94 SPHK1 (0.51) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL1713289 0.94 SPHK1 (0.51) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL7752407 0.94 SPHK1 (0.51) CYP2C9MAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119143609-B Preparation method of alkyl cyclohexyl benzidine 中节能万润股份有限公司 2025-03-21 CN disclosed
CN-119143609-A Preparation method of alkyl cyclohexyl benzidine 中节能万润股份有限公司 2024-12-17 CN disclosed
WO-2023012202-A1 SWITCHING LAYERS FOR USE IN A WINDOW ELEMENT MERCK PATENT GMBH (DE) 2023-02-09 WO disclosed
US-9309455-B2 Indeno-fused ring compounds TRANSITIONS OPTICAL, INC. (US) 2016-04-12 US disclosed
EP-2652552-B9 PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS TRANSITIONS OPTICAL INC (US) 2016-02-17 EP disclosed
EP-2652552-B1 PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS TRANSITIONS OPTICAL INC (US) 2015-09-02 EP disclosed
US-20140166948-A1 INDENO-FUSED RING COMPOUNDS TRANSITIONS OPTICAL LIMITED (IE) 2014-06-19 US disclosed
US-8698117-B2 Indeno-fused ring compounds TRANSITIONS OPTICAL, INC. (US) 2014-04-15 US disclosed
US-8545984-B2 Photochromic compounds and compositions TRANSITIONS OPTICAL, INC. (US) 2013-10-01 US disclosed
US-20120126185-A1 INDENO-FUSED RING COMPOUNDS TRANSITIONS OPTICAL, INC. (US) 2012-05-24 US disclosed
US-20110129678-A1 Photochromic compounds and compositions TRANSITIONS OPTICAL, INC. (US) 2011-06-02 US disclosed
US-4545922-A Liquid crystalline fluorine-containing cyclohexylbiphenyls and dielectrics and electro-optical display elements based thereon MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1985-10-08 US disclosed
EP-0051738-B1 CYCLOHEXYL-BIPHENYL DERIVATIVES THAT CONTAIN FLUOR, DIELECTRICS CONTAINING THEM AND ELECTRO-OPTICAL INDICATING ELEMENT MERCK PATENT GmbH (DE) 1984-07-25 EP disclosed
US-4456545-A Dichroitic anthraquinone dyestuffs useful in liquid crystalline dielectrics and electro-optical indicator elements MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1984-06-26 US disclosed
US-4415470-A HIGH SPEED SWITCHING MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1983-11-15 US disclosed
EP-0051738-A1 Cyclohexyl-biphenyl derivatives that contain fluor, dielectrics containing them and electro-optical indicating element MERCK PATENT GmbH (DE) 1982-05-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110129678-A1 Photochromic compounds and compositions CRY2, CRY1, PPOX CYP2C9 167/4885MAPT 573/4885MEN1 3110/4885
US-20120126185-A1 INDENO-FUSED RING COMPOUNDS CRY2, SQOR, INTS6 CYP2C9 88/4885MAPT 2624/4885MEN1 3740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.