SCHEMBL9749361

SCHEMBL9749361

Cc1ccccc1NC(=O)c1cc2ccc3c4ccccc4[nH]c3c2cc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.67
▸ KDM4E B2RXH2 5/20 0.67
▸ MEN1 O00255 4/20 0.67
▸ KMT2A Q03164 4/20 0.67
▸ CACNA1B Q00975 1/20 0.67
▸ APBA1 Q02410 1/20 0.67
▸ MPL P40238 4/20 0.65
▸ LMNA P02545 3/20 0.48
▸ HTT P42858 2/20 0.48
▸ ALDH1A1 P00352 1/20 0.48
▸ HPGD P15428 1/20 0.48
▸ MAPK1 P28482 1/20 0.48
▸ HSD17B10 Q99714 1/20 0.48
▸ PLA2G7 Q13093 1/20 0.47
▸ POLB P06746 2/20 0.46
▸ PARP14 Q460N5 4/20 0.46
▸ NPC1 O15118 1/20 0.46
▸ NPY1R P25929 1/20 0.46
▸ NPY2R P49146 1/20 0.46
▸ RAB9A P51151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10983073 0.91 MEN1 (0.63) MAPTKDM4EMEN1KMT2ACACNA1B
SCHEMBL10980076 0.91 KMT2A (0.63) MAPTKDM4EMEN1KMT2ACACNA1B
SCHEMBL10978232 0.89 KDM4E (0.63) MAPTKDM4EMEN1KMT2ACACNA1B
SCHEMBL10426529 0.89 MAPT (0.54) MAPTKDM4EMEN1KMT2ACACNA1B
SCHEMBL5815835 0.87 MEN1 (0.64) MAPTKDM4EMEN1KMT2ACACNA1B
SCHEMBL31707424 0.87 KMT2A (0.76) MAPTKDM4EMEN1KMT2ACACNA1B
SCHEMBL5819536 0.87 KMT2A (0.76) MAPTKDM4EMEN1KMT2ACACNA1B
SCHEMBL9358087 0.86 KMT2A (0.66) MAPTKDM4EMEN1KMT2ACACNA1B
SCHEMBL10987424 0.85 KMT2A (0.79) MAPTKDM4EMEN1KMT2ACACNA1B
SCHEMBL175806 0.84 KMT2A (0.78) MAPTKDM4EMEN1KMT2ACACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4236267-A — — None — — JP disclosed
JP-57203061-A — — None — — JP disclosed
JP-H04236267-A BISAZO COMPOUND RICOH CO LTD 1992-08-25 — — JP disclosed
US-4692393-A ELECTROPHOTOGRAPHY KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1987-09-08 — — US disclosed
US-4507471-A CHARGE TRANSFER COMPOUNDS FOR ELECTROPHOTOGRAPHIC ELECMENTS RICOH COMPANY, LTD. (JP) 1985-03-26 — — US disclosed
JP-S57203061-A NOVEL TRISAZO COMPOUND AND ITS PREPARATION RICOH CO LTD 1982-12-13 — — JP disclosed
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