Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 5/20 | 0.50 |
| ▸ | DRD2 | P14416 | 4/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749071 | 0.86 | CYP3A4 (0.44) | DRD3DRD2DRD4CYP3A4ALDH1A1 | |
| SCHEMBL16448789 | 0.86 | CYP3A4 (0.44) | DRD3DRD2DRD4CYP3A4ALDH1A1 | |
| SCHEMBL8402494 | 0.83 | DRD3 (0.43) | DRD3DRD2DRD4CYP3A4ALDH1A1 | |
| SCHEMBL10460570 | 0.83 | DRD3 (0.45) | DRD3DRD2DRD4CYP3A4ALDH1A1 | |
| SCHEMBL28279575 | 0.81 | PPARG (0.52) | HTR1AHTR1DHTR2C | |
| SCHEMBL13981216 | 0.81 | HTR1A (0.51) | ALDH1A1HSD17B10GAAMAPTHTR1A | |
| SCHEMBL9627835 | 0.81 | DRD3 (0.46) | DRD3DRD2DRD4CYP3A4ALDH1A1 | |
| SCHEMBL9627834 | 0.79 | DRD3 (0.45) | DRD3DRD2DRD4CYP3A4ALDH1A1 | |
| SCHEMBL24298845 | 0.79 | DRD3 (0.43) | DRD3DRD2DRD4CYP3A4ALDH1A1 | |
| SCHEMBL29288526 | 0.79 | HTR1A (0.43) | DRD3DRD2DRD4CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230475-B1 | NOVEL UREA DERIVATIVES, PROCESSES FOR PRODUCTION THEREOF AND HERBICIDE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4838924-A | NONPHYTOTOXIC | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-13 | — | — | US | disclosed |