Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | PARP1 | P09874 | 1/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.65 |
| ▸ | HTR2B | P41595 | 2/20 | 0.65 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.65 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.65 |
| ▸ | HTR1A | P08908 | 1/20 | 0.65 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.65 |
| ▸ | DRD2 | P14416 | 1/20 | 0.65 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.65 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.65 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.65 |
| ▸ | DRD1 | P21728 | 1/20 | 0.65 |
| ▸ | DRD4 | P21917 | 1/20 | 0.65 |
| ▸ | DRD5 | P21918 | 1/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5066512 | 1.00 | HRH1 (0.67) | HRH1LMNAPARP1KCNH2HTR2B | |
| SCHEMBL5060455 | 1.00 | HRH1 (0.67) | HRH1LMNAPARP1KCNH2HTR2B | |
| SCHEMBL30783267 | 1.00 | HRH1 (0.67) | HRH1LMNAPARP1KCNH2HTR2B | |
| SCHEMBL5061666 | 0.94 | HRH1 (0.60) | HRH1LMNAPARP1 | |
| SCHEMBL9750054 | 0.94 | HRH1 (0.60) | HRH1LMNAPARP1 | |
| SCHEMBL5060511 | 0.94 | HRH1 (0.60) | HRH1LMNAPARP1 | |
| SCHEMBL9749424 | 0.90 | HRH1 (0.65) | HRH1LMNAKCNH2HTR2BSLC22A1 | |
| SCHEMBL5064807 | 0.90 | HRH1 (0.65) | HRH1LMNAKCNH2HTR2BSLC22A1 | |
| SCHEMBL9750385 | 0.90 | HRH1 (0.55) | HRH1LMNAPARP1 | |
| SCHEMBL5056419 | 0.90 | HRH1 (0.65) | HRH1LMNAKCNH2HTR2BSLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116863-A | Antiallergens, antiinflammatory agents; asthma | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |