Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.74 |
| ▸ | HRH1 | P35367 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749932 | 0.90 | HRH1 (0.66) | AKR1B1HRH1LMNATBXA2R | |
| SCHEMBL31254018 | 0.89 | AKR1B1 (0.82) | AKR1B1HRH1LMNATBXA2RLTB4R | |
| Oxepinac SCHEMBL106088 | 0.85 | AKR1B1 (1.00) | AKR1B1HRH1LMNA | |
| Oxepinac SCHEMBL31563425 | 0.85 | AKR1B1 (1.00) | AKR1B1HRH1LMNA | |
| SCHEMBL9749904 | 0.85 | AKR1B1 (0.55) | AKR1B1HRH1LMNA | |
| Isoxepac SCHEMBL24970 | 0.77 | AKR1B1 (0.81) | AKR1B1HRH1LMNA | |
| Isoxepac SCHEMBL29588437 | 0.77 | AKR1B1 (0.81) | AKR1B1HRH1LMNA | |
| SCHEMBL5060821 | 0.77 | AKR1B1 (0.64) | AKR1B1HRH1LMNA | |
| SCHEMBL5060820 | 0.77 | AKR1B1 (0.64) | AKR1B1HRH1LMNA | |
| SCHEMBL9750101 | 0.77 | AKR1B1 (0.64) | AKR1B1HRH1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116863-A | Antiallergens, antiinflammatory agents; asthma | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |