Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.64 |
| ▸ | HRH1 | P35367 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5060821 | 1.00 | AKR1B1 (0.64) | AKR1B1HRH1LMNAPARP1 | |
| SCHEMBL5060820 | 1.00 | AKR1B1 (0.64) | AKR1B1HRH1LMNAPARP1 | |
| SCHEMBL5056479 | 0.94 | AKR1B1 (0.61) | AKR1B1HRH1LMNAPARP1 | |
| SCHEMBL5056486 | 0.94 | AKR1B1 (0.61) | AKR1B1HRH1LMNAPARP1 | |
| SCHEMBL9749982 | 0.94 | AKR1B1 (0.61) | AKR1B1HRH1LMNAPARP1 | |
| SCHEMBL5056472 | 0.92 | HRH1 (0.66) | AKR1B1HRH1LMNAPARP1 | |
| SCHEMBL5056474 | 0.92 | HRH1 (0.66) | AKR1B1HRH1LMNAPARP1 | |
| SCHEMBL8782255 | 0.92 | HRH1 (0.66) | AKR1B1HRH1LMNAPARP1 | |
| SCHEMBL9750044 | 0.89 | AKR1B1 (0.49) | AKR1B1HRH1LMNAPARP1 | |
| SCHEMBL5060352 | 0.89 | AKR1B1 (0.49) | AKR1B1HRH1LMNAPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116863-A | Antiallergens, antiinflammatory agents; asthma | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |