Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10764164 | 1.00 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL13684205 | 0.83 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL17956525 | 0.82 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL6991879 | 0.82 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL11071581 | 0.82 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL18154139 | 0.81 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL12130679 | 0.81 | KMT2A (0.50) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL9232077 | 0.80 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL3861086 | 0.79 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL17747886 | 0.78 | CCR6 (0.48) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219852-B1 | CHARTREUSIN DERIVATIVES, SALTS THEREOF, ANTITUMOROUS COMPOSITIONS CONTAINING THE SAME, AND PROCESSES FOR PRODUCING THE SAME | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1992-02-05 | — | — | EP | disclosed |
| US-5064945-A | Antitumor Agents | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1991-11-12 | — | — | US | disclosed |
| US-4927919-A | ANTITUMOR AGENTS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1990-05-22 | — | — | US | disclosed |
| EP-0159708-B1 | CHARTREUSIN DERIVATIVES, SALTS THEREOF, ANTITUMOROUS COMPOSITIONS CONTAINING THE SAME, AND PROCESSES FOR PRODUING THE SAME | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1989-12-13 | — | — | EP | disclosed |
| US-4760136-A | Chartreusin derivatives and salts thereof | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1988-07-26 | — | — | US | disclosed |
| EP-0159708-A2 | Chartreusin derivatives, salts thereof, antitumorous compositions containing the same, and processes for produing the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1985-10-30 | — | — | EP | disclosed |